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IB Biology · Form and function

Proteins practice questions.

48 exam-style questions on Proteins — topic B1.2 of Form and function in the IB Biology syllabus — with answers and explanations. Samples below; the full set is free with an account.

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About this topic

Syllabus code
B1.2
Subject
IB Biology
Theme
B · Form and function
Questions
48 with worked answers
Question types
18 multiple-choice questions · 10 flashcards · 9 fill-in-the-gap questions · 7 true/false questions · 2 diagram tasks · 2 matching tasks
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Sample questions on Proteins

The monomers from which proteins are built are

  • glucose molecules
  • amino acids
  • fatty acids
  • nucleotides

Answer: amino acids

Amino acids join by peptide bonds (condensation) to form polypeptides.

State the type of bond that links adjacent amino acids in the primary structure of a protein.

  • Hydrogen bond
  • Peptide bond
  • Disulfide bond
  • Glycosidic bond

Answer: Peptide bond

Amino acids are joined by peptide bonds, formed by condensation between the amino group of one and the carboxyl group of the next.

Determine what distinguishes one amino acid from another.

  • The amino group
  • The carboxyl group
  • The variable R group
  • The central carbon atom

Answer: The variable R group

All amino acids share an amino group, a carboxyl group and a central carbon; only the variable R group differs, giving each amino acid its properties.

Which bond between R groups helps stabilise the tertiary structure of a globular protein containing cysteine residues?

  • Peptide bonds along the backbone
  • Covalent disulfide bridges
  • Glycosidic bonds
  • Ester bonds

Answer: Covalent disulfide bridges

Tertiary structure is stabilised by R-group interactions, including strong covalent disulfide bridges between the sulfur-containing R groups of cysteine residues.

Explain why boiling an egg white causes it to become solid and opaque.

  • New peptide bonds form between proteins
  • Proteins denature and unfold
  • The primary structure sequence changes
  • Proteins polymerise into carbohydrates

Answer: Proteins denature and unfold

Heat disrupts the hydrogen bonds, ionic bonds and other interactions maintaining tertiary/quaternary structure, so proteins denature, unfold and aggregate; the primary sequence is unchanged.

Distinguish fibrous from globular proteins by determining which statement is correct.

  • Globular proteins are structural and insoluble; fibrous are enzymes
  • Fibrous proteins are structural, insoluble; globular soluble
  • Both are always soluble in water
  • Fibrous proteins have only primary structure

Answer: Fibrous proteins are structural, insoluble; globular soluble

Fibrous proteins (e.g. collagen) are elongated, structural and insoluble; globular proteins (e.g. enzymes, haemoglobin) are compact, usually water-soluble and have metabolic/functional roles.

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